Structure, stability and elasticity of DNA nanotube

DNA nanotubes are tubular structures composed of DNA crossover molecules. We present a bottom up approach for construction and characterization of these structures. Various possible topologies of nanotubes are constructed such as 6-helix, 8-helix and tri-tubes with different sequences and lengths. We have used fully atomistic molecular dynamics simulations to study the structure, stability and elasticity of these structures. Several nanosecond long MD simulations give the microscopic details about DNA nanotubes. Based on the structural analysis of simulation data, we show that 6-helix nanotubes are stable and maintain their tubular structure; while 8-helix nanotubes are flattened to stabilize themselves. We also comment on the sequence dependence and effect of overhangs. These structures are approximately four times more rigid having stretch modulus of ~4000 pN compared to the stretch modulus of 1000 pN of DNA double helix molecule of same length and sequence. The stretch moduli of these nanotubes are also three times larger than those of PX/JX crossover DNA molecules which have stretch modulus in the range of 1500-2000 pN. The calculated persistence length is in the range of few microns which is close to the reported experimental results on certain class of the DNA nanotubes.Comment: Published in Physical Chemistry Chemical Physic

शिवमंगल सिंह 'सुमन' के काव्य का विचार-पक्ष

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Traditional Family History & Training - Part 1

While Ayurveda is an ancient system of medicine, training for it involves many years of study as well as apprenticeship. The apprenticeship could run in the family, as from father to son, or in a more formal setting, as with an acclaimed teacher. This apprenticeship could go on for decades, or till such time that the teacher felt confident in the abilities of his student. In modern times, universities and colleges in India have instituted formal certificates, diplomas and degrees in this traditional art and science of medicine. These formal degrees can range from one to three years. They may also include curriculum on modern forms of medicine to fill the gaps that traditional medicine may have. Presented here are narratives of how long it takes to become good in Ayurvedic practice.Asian StudiesSouth Asia InstituteHindi Urdu Flagshi

Ayurvedic Treatment & Nutrition

Diagnosis in Ayurveda is based on the ancient conception of ailments in the body generated by three primary kinds of elemental humours: those that accrue from kapha (phlegm), those that are generated by pitta (bile) and, those that result from imbalance of the vata (air). The primary cause of an ailment in the body is regarded as an imbalance between these three fundamental elements. Diagnosis, again, involves three kinds of preliminary tests: by examining the pulse, by looking at the physical features of the patient, and by asking pertinent questions to the patient. While this may sound fairly simple, the exact method of examining the pulse, for example, comes from a long period of experience. Similarly, drawing conclusions from the physical appearance of the patient requires a lot of knowledge and experience. These video clips throw some light on how Ayurvedic doctors use this knowledge for patient treatment.Asian StudiesHindi Urdu FlagshipSouth Asia Institut

Faith & Disease

Unani (also spelt Yunani) refers to the tradition of Graeco-Arabic medicine. Like Ayurveda, this also a comprehensive tradition of medicine that goes back of Hippocrates, but owes a lot to the wisdom and experience of Arabic and Persian physicians. India remains one of the most prominent countries encouraging research and education in the field of Unani medicine. Listening to the Unani video clips will make the students aware of not only the concepts used in Unani medicine, but also the integral role of faith in healing.Asian StudiesSouth Asia InstituteHindi Urdu Flagshi

Faith in the Doctor

Asian StudiesHindi Urdu FlagshipSouth Asia Institut

Faith in Unani

Unani (also spelt Yunani) refers to the tradition of Graeco-Arabic medicine. Like Ayurveda, this also a comprehensive tradition of medicine that goes back of Hippocrates, but owes a lot to the wisdom and experience of Arabic and Persian physicians. India remains one of the most prominent countries encouraging research and education in the field of Unani medicine. Listening to the Unani video clips will make the students aware of not only the concepts used in Unani medicine, but also the integral role of faith in healing.Asian StudiesSouth Asia InstituteHindi Urdu Flagshi

Comparing Ayurveda & Conventional Medicine

South Asia in general, and India specifically, are regions with immense diversity in culture and language. Because of this conversations about medicine between doctors and patients takes different forms from one region to another. This is especially true when we look at urban, suburban and rural doctor-patient interactions. Added to these is the element of gender. Owing to the somewhat conservative worldview of gender interactions, even doctor-patients conversations might become colored by it. The clips in this section show variations of patterns of conversation in the practice of conventional medicine.Asian StudiesHindi Urdu FlagshipSouth Asia Institut

Unga Method of Use

Description of the preparation of uses of the Unga plant. Herbs like Amla, Black Dhatura, Karanj, Unga etc. are basic herbs used in Ayurveda for treating numerous ailments. There is a well prescribed process of preparing herbs for medicinal purposes. This process may include cutting, chopping, peeling, drying, leaching and mixing with other herbs before they can be used for treatment. The Ayurvedic doctor has to be very familiar with these processes to prepare the right kind of herbal medicine. Various parts of the same plant may require collection and preparation at different periods of time. The knowledge of this process of medicine preparation can be passed on from father to son, or taught in a formal course of study. Here are vignettes of how some of these are prepared for medicinal use.xAsian StudiesSouth Asia InstituteHindi Urdu Flagshi

Why People Visit Allopathic Doctors

South Asia in general, and India specifically, are regions with immense diversity in culture and language. Because of this conversations about medicine between doctors and patients takes different forms from one region to another. This is especially true when we look at urban, suburban and rural doctor-patient interactions. Added to these is the element of gender. Owing to the somewhat conservative worldview of gender interactions, even doctor-patients conversations might become colored by it. The clips in this section show variations of patterns of conversation in the practice of conventional medicine.Asian StudiesHindi Urdu FlagshipSouth Asia Institut